OSM2000 Freezing point Osmotic pressure tester with independent research and development is in accordance with Raoul freezing point theory, based on the solution freezing point declined value proportional to the solution molar concentration, using high sensitivity of temperature-sensing element, to measure the freezing point of different solutions, so as to derive the osmotic pressure molar concentration. This theory has been widely used for the test and research of osmotic pressure molar concentration in the fields such as pharmaceuticals, pharmaceutical analysis, biological and food therapy.
Main features
1. Humanized design, 7-inch color touch screen, Chinese interface, easy and quick operation.
2. It has the functions of electronic signature and user classification management, to satisfy CFR PART21 store data query according to time which can store 3 years of testing data.
3. It can carry on single-point or multi-point (31-point) linear calibration, to ensure that the instrument has the detection accuracy of each range interval in stability.
4. Temperature probe adopts the screw linear guide motor d esign, so that the operation just on a touch screen can complete the whole test process.
5. It is equipped with high precision sensor, which has high measuring accuracy and good reproducibility.
6. It adopts double refrigeration system, with a short pre-cooling time, fast detection speed, to facilitate continuous detection.
7. A small amount of test sample can meet the demand in different areas.
8. It can simultaneously display the osmotic pressure molar concentration value, the freezing point value and the molar concentration ratio.
9. The cooling system adopts the a thermal transfer fluid design, to exempt from frequent maintenance.
10. Built-in “Chinese pharmacopoeia” hundreds of injectable drug name can facilitate the preset information of test sample.
Technical parameters
| Model | OSM2000 Osmotic pressure tester |
| Measurement range | 0~2000 mOsmol/kg |
| Resolution ratio | 0.1 |
| Sample amount | 100μl |
| Testing duration | ≤3min |
| Pre-cooling time | ≤3min |
| Measurement error | ≤1% |
| Repeatability | ≤1% |
| Linearity | ≤1% |
| Environment temperature | 0~30℃ Recommended for 15~25℃ |
| Environment temperature | ≤60% |
| Power supply | 220V～ 50Hz 150VA |
| Overall dimensions | 221*275*345 (mm) |
| Weight | 16 kg |
Preparation of standard solution
According to the mmol osmotic pressure molar concentration in weight for each standard solution as shown in Table 1, weigh the amount of sodium chloride, which is dried at the temperature of 500~650ºC for 40-50 minutes and placed in the dryer and cooled down to the room temperature, and place such sodium chloride in the measuring flask containing 100g of water, and then shake up.
| Freezing-point osmometer standard solution mOsmol/kg water | Weight of sodium chloride G | Decrease value of freezing point Δt (ºC) |
| 100 | 0.3087 | 0.1858 |
| 200 | 0.6260 | 0.3716 |
| 300 | 0.9463 | 0.5574 |
| 400 | 1.2684 | 0.7432 |
| 500 | 1.5916 | 0.9290 |
| 600 | 1.9147 | 1.1148 |
| 700 | 2.2380 | 1.3006 |
| 750 | 2.398 | 1.3935 |
| 1000 | 3.223 | 1.8580 |
Table 1
