BIOF-S Classic Series Classic Automatic Stainless Steel Fermenter Bioreactor

Body material: 316L stainless steel, jacket 304 stainless steel;

With special sampling valve for fermentation tank, bottom discharge valve, with side Large-view mirror, 12V safety Philips lighting, with Temperature, pH, DO, defoaming port, acid and alkali replenishment port, inoculation port, feed port, air inlet, exhaust port, seed transfer port, liquid level electrode, defoaming electrode, etc.;

Internal polishing accuracy Ra0.4, external polishing accuracy is Ra0.6, and all welds are firm, neat and beautiful.

Top-type mechanical stirring system, adopts special 316L stainless steel for stirring shaft, AD mechanical seal (a special mechanical seal system that can meet higher fermentation requirements);

Adopts adjustable 2-stage 6-inclined blade stirring paddle, 1-stage compression type high-efficiency Bubble paddle, 4-level detachable baffle;

Primary filtration, 0.01μm precision sterilization filter, fine filter selection of high-quality products, to ensure safety and independent sterilization, greatly extending the service life; annular gas distribution at the bottom Device

Control range: 2-12pH, display range: 0-14pH,

Control accuracy: ±0.02pH, resolution: 0.01pH;

Control: Intelligent PID control, abnormal pH value alarm, segment control, data can be uploaded to the host computer

Control range: 0-100%, display range: 0-200%,

Control accuracy: ±5%, resolution: 0.1%;

Control: Intelligent PID control, abnormal DO value alarm, data can be uploaded to the host computer

Intelligent PID control not only ensures the rapidity of temperature control, but also realizes energy saving.

Temperature control: cooling water temperature +5℃-65℃±0.2℃, display temperature: 0-150℃±0.1℃ Fermentation process sequence control (set according to fermentation time zone, temperature automatic variable control, at least 10 sections)

Highly sensitive defoaming electrode

Control method: time and proportion automatic control

Flow control: rotameter, Siemens module, MFC auto flow control is optional

Air filtration: pre-main pre-filter, secondary air inlet filter (the filter can be sterilized independently).

Fine filtration, the filter shell is made of 304 stainless steel, the filter element filtration effect can reach the sterile filtration level, the filter element material is hydrophobic polytetrafluoroethylene or other suitable materials, the sterilization filter has an online integrity test port, and each sterilization filter has an independent Online sterilization process.

Pre-filter, filter housing is made of 304 stainless steel.

Intake control: rotameter. The air intake pipeline has a diaphragm valve that can be manually opened and closed.

Check device: There is a check device to prevent the valve from being sucked back by materials.

Pressure display: displays the pressure of ventilation and sterilization process with an accuracy of 0.01MPa

Drainage: The filter is designed with a drainage device and has measures to prevent back suction.

Exhaust: The exhaust is manually controlled by a pneumatic diaphragm valve; the gas is filtered and discharged, and the filter shell is made of 304 stainless steel.

Sterilization requirements: Filters, inlet and exhaust pipelines can be steam sterilized online

Ventilation: Rotameter control, adjust and control the flow of each gas according to process requirements, the maximum ventilation flow is 2VVM. The air system consists of pre-filter, flow meter, air fine filter, diaphragm valve, and check valve.

Steam filtration precision: 1um.

Maximum design flow is about 2VVM, and the control accuracy is ±0.5%

Control method: Auto control

Pressure gauge auxiliary display, control range: 0-0.4MPa, high temperature resistant and high-precision pressure sensor is used to accurately detect the fermentation tank pressure, the regulating valve automatically adjusts the tank pressure. Pressure measurement range: 0-0.35Mpa, ±0.3%, control accuracy :±0.5%

Equipped with a complete replenishment system, the replenishment can be measured;

Number of peristaltic pumps can be selected according to needs, and conventional configuration is four.

The role of the peristaltic pump can be selected and set on the control interface, which makes the user more convenient and flexible in actual use.

Equipped with specially designed replenishment pins to ensure the safe operation of replenishment.

Sterilization temperature: 100-130℃;

The rationality of the design ensures the safe realization of the transfer

The pipeline is made of stainless steel with precision polished; argon gas shielded welding; meets GMP requirements

The stainless steel table frame is used, and the bottom is installed with pulleys for easy movement

hot water tank

Diaphragm pump

CIP Outlet Pump

CIP cleaning return pump

liquid level sensor

Temperature Sensor

conductivity meter

Manual butterfly valve

Pneumatic Butterfly Valve

Control cabinet